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Coming Together for Major Depressive Disorder

Consider joining our MDD study in Fort Worth

Help Advance Research for Major Depressive Disorder

Join a Clinical Research Study for Adults with Depression in Texas

If you live in or near the Fort Worth, Texas area, are between 18 and 75 years old, and have been diagnosed with major depressive disorder (MDD), you may be able to participate in a clinical research study.

This study is for adults living with major depressive disorder who are currently taking standard-of-care medication for depression. Researchers are studying whether an investigational medication, when added to a participant’s current treatment, may help support people living with MDD compared with placebo (a treatment with no active ingredients).

Participants who qualify will continue their current depression treatment while taking part in the study. The investigational study medication or placebo will be self-administered as part of the research study.

There is no cost to participate. All study-related care and evaluations are provided as part of the research study. Compensation or reimbursement for study-related time and travel may be available.

Participation is voluntary, and you may choose to stop participating at any time.

This is a research study and is not intended to replace your current medical care.

Why Participate?

Help Advance Depression Research

By taking part, you can contribute to clinical research focused on evaluating potential new treatment approaches for adults living with major depressive disorder.

Ongoing Monitoring Throughout the Study

Participants receive regular study-related monitoring, assessments, and check-ins with the study team throughout participation in the study.

Continue Current Depression Treatment

Participants will remain on their current standard-of-care medication for major depressive disorder while participating in the study, as determined by the study doctor.

No Cost to Participate

All study-related visits, assessments, and procedures are provided at no cost. Reimbursement for study-related time and reasonable travel expenses may also be available.

What’s Involved?

If eligible and choose to participate, you may be asked to:

    • If you are eligible and choose to participate, you may be asked to:

      • Continue taking your current standard-of-care medication for major depressive disorder, as confirmed by the study doctor
      • Be randomly assigned to receive either the investigational study medication or placebo in addition to your current treatment
      • Self-administer the study medication as instructed by the study team
      • Store and use the blinded study medication as directed
      • Complete study questionnaires and electronic or paper diaries throughout participation
      • Attend required study visits and follow study procedures during the study
      • Participate in a double-blind study, meaning neither you nor the study staff will know whether you receive the investigational medication or placebo
      • Remain in the study for up to approximately 15 months, including screening, treatment, and follow-up periods

Who May Be Eligible?

You may qualify if you:

  • Are between 18 and 75 years old
  • Have been diagnosed with major depressive disorder (MDD)
  • Are currently taking a stable standard-of-care medication for depression
  • Have experienced multiple major depressive episodes
  • Are willing and able to attend required study visits and follow study procedures
  • Are willing to complete study questionnaires and electronic or paper diaries during participation

You may not be eligible if you:

  • Have certain psychiatric conditions such as schizophrenia, bipolar disorder, borderline personality disorder, or eating disorders
  • Have a recent history of moderate or severe substance or alcohol use disorder
  • Are considered a significant risk for suicide
  • Have certain medical conditions, including type 1 diabetes or a history of pancreatitis
  • Have experienced certain recent cardiovascular events such as heart attack, stroke, chest pain, or hospitalization for congestive heart failure
  • Have recently participated in another clinical research study involving investigational treatment
  • Are unable or unwilling to comply with study requirements
Final eligibility will be determined by the study team after additional screening.

 

Ready to Learn More?

If you are interested, please complete the intake form on this page. A member of the study team will review your information and contact you to discuss next steps.

Submitting the form does not obligate you to participate—it’s simply the first step in learning more.

A member of the study team will be available to answer your questions and support you throughout the screening process.

Study Site Locations:

Cognition Health - Fort Worth
1307 8th Avenue Fort Worth Texas 76104

Questions?

Additional information about this study may be available through participating locations listed below.

For Texas Residents:

Best Value West Pharmacy
Burleson, TX

Best Value Ridglea Drug
Fort Worth, TX

Best Value Country Day
Fort Worth, TX

Best Value Rhome Pharmacy
Rhome, TX